Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

African Americans have higher average Lp(a) levels and are more likely to have heart disease than non-Hispanic whites, but there is not enough information on Lp(a) and cardiovascular disease risk in this population.

News | Cardiovascular Clinical Studies

Heart Study’s Goal: Better Understand and Serve the Underrepresented

August 10, 2023 — Cardiovascular disease is the number one killer of all Americans. Yet, African Americans are 30% more ...

August 10, 2023

Game-changing potential for drug testing and cardiovascular disease treatments - Tiny Heart Model carries massive implications

News | Cardiovascular Clinical Studies

Tiny, Multichambered Human Heart Model Developed by Hebrew University Researchers Could Transform Cardiovascular Research and Drug Evaluation

August 9, 2023 — A team of researchers, led by the Hebrew University of Jerusalem (HU), has developed a tiny human heart ...

August 09, 2023

Novo Nordisk A/S: Semaglutide 2.4 mg reduces the risk of major adverse cardiovascular events by 20% in adults with overweight or obesity in the SELECT trial

News | Cardiovascular Clinical Studies

Major Adverse Cardiovascular Events Reduced in Overweight/Obese Patients with Wegovy, per SELECT Trial

August 9, 2023 — Novo Nordisk announced the headline results from the SELECT cardiovascular outcomes trial. The double ...

August 09, 2023

Although at greater risk, a new study found that patients of African ancestry with dilated cardiomyopathy (DCM) were less likely to have clinically actionable variants in DCM genes than those of European ancestry.

News | Cardiovascular Clinical Studies

Study Reveals Significant Difference in Cardiomyopathy Genes Between Black and White Patients

August 8, 2023 — Although at greater risk, a new study found that patients of African ancestry with dilated ...

August 08, 2023

The medication, known as a “polypill,” includes three active ingredients (acetylsalicylic acid, ramipril, and atorvastatin)

News | Nuclear Imaging

World Health Organization Includes the Cardiovascular Polypill in its list of Essential Medicines after a Groundbreaking Study Led by the President of Mount Sinai Heart

August 3, 2023 — The cardiovascular polypill, developed by the Spanish National Centre for Cardiovascular Research (CNIC ...

August 03, 2023

Merit’s WAVE study is a prospective, randomized, controlled, multicenter study

News | Cardiovascular Clinical Studies

Merit Medical’s WRAPSODY Arteriovenous Access Efficacy (WAVE) Pivotal Study Completes Enrollment

August 3, 2023 — Merit Medical Systems, a leading global manufacturer and marketer of healthcare technology, today ...

August 03, 2023

India clinical trial commences with first 30 cases

News | Heart Valve Technology

First Patients Outside of U.S. Treated with TRIA Polymer Surgical Mitral Heart Valve

August 2, 2023 — Foldax , Inc., a leader in the development of innovative, polymer heart valves, today announced that ...

August 02, 2023

LX2020 preclinical studies demonstrated proof-of-concept with treatment restoring desmosomal integrity, reducing arrhythmias, and extending survival in a clinically relevant murine model

News | Pharmaceuticals

LEXEO Therapeutics Announces FDA Clearance of IND for LX2020, an AAV-based Gene Therapy Candidate for PKP2 Arrhythmogenic Cardiomyopathy

August 1, 2023 —LEXEO Therapeutics, a clinical-stage gene therapy company advancing adeno-associated virus (AAV)-based ...

August 01, 2023

AI demonstrated high accuracy, reduced non-diagnostic outputs, and identified HFpEF patients with worse outcomes.

News | Cardiovascular Clinical Studies

Study Confirms Ultromics' AI Can Improve HFpEF Detection Using a Single Echocardiogram View

July 31, 2023 — Applying AI to a single apical four chamber (A4C) view echocardiogram provides accurate information to ...

July 31, 2023

Primary endpoints across three studies underscore the importance of accuracy, utility, and efficiency in coronary artery disease diagnostics and clinical decision making

News | Cardiovascular Clinical Studies

HeartFlow to Announce New Data at SCCT23

July 28, 2023 — Respective results from the REVEALPLAQUE, DECODE, and SMART-CT clinical studies demonstrate the accuracy ...

July 28, 2023

A multi-institutional team of scientists led by Dr. Mario Gaudino, the Stephen and Suzanne Weiss Professor in Cardiothoracic Surgery and assistant dean for clinical trials at Weill Cornell Medicine, has been approved for a nearly $30 million funding award from the Patient-Centered Outcomes Research Institute (PCORI).

News | Cardiovascular Clinical Studies

Large PCORI Award Funds Study of Surgical Options for Coronary Artery Disease in Underrepresented Patient Populations

July 25, 2023 — A multi-institutional team of scientists led by Dr. Mario Gaudino, the Stephen and Suzanne Weiss ...

July 25, 2023

BioCardia, Inc., a developer of cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary disease, announced that the independent Data Safety Monitoring Board (DSMB) has completed its prespecified data review for the ongoing Phase III pivotal CardiAMP Cell Therapy Heart Failure Trial

News | Cardiovascular Clinical Studies

BioCardia Announces DSMB Recommendation to Pause New Enrollment in Phase III Pivotal CardiAMP Cell Therapy Heart Failure Trial While Additional Blinded Data is Collected

July 24, 2023 — BioCardia, Inc., a developer of cellular and cell-derived therapeutics for the treatment of ...

July 24, 2023

SmartfIRE study is evaluating THERMOCOOL SMARTTOUCH SF Dual Energy Catheter’s potential to enable safe and simple procedures with the ability to deliver both radiofrequency (RF) and pulsed field ablation (PFA)

News | Atrial Fibrillation

Biosense Webster Completes Enrollment in Pivotal Trial Evaluating PFA and RF Dual Energy Catheter for Patients with Atrial Fibrillation in Europe

July 21, 2023 — Biosense Webster, Inc., a global leader in cardiac arrhythmia treatment and part of Johnson & Johnson ...

July 21, 2023

Pilot study will assess positive impacts of real-time safety monitoring on patient outcomes and treatment experience

News | Remote Monitoring

AliveCor and Thomas Jefferson University Hospital Partner to Evaluate KardiaMobile 6L for QT Prolongation Screening in Patients Treated for Opioid Use Disorder

July 21, 2023 — AliveCor, a leading innovator in FDA-cleared personal electrocardiogram (ECG) technology, today ...

July 21, 2023

Bicêtre Hospital in Paris, France, and Baptist Stroke & Cerebrovascular Center in Jacksonville, Florida, USA, join global network of leading stroke centers as part of WE-TRUST multicenter clinical trial to evaluate the potential benefits of a Direct to Angio Suite treatment pathway for stroke patients

News | Stroke

First Patients in France and the USA Enrolled in Global WE-TRUST Trial to Accelerate Stroke Diagnosis and Treatment

July 20, 2023 — The first patients in France and the USA have been enrolled into the large-scale WE-TRUST* multicenter ...

July 20, 2023