Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

Initial data indicate that DSR 2.0 is safe and well tolerated, restores diuretic response and improves cardiorenal status
News | Heart Failure
Sequana Medical Announces Initial Positive Data from MOJAVE, a US Phase 1/2a Study of DSR 2.0 for Treatment of Heart Failure Through Breaking Vicious Cycle of Cardiorenal Syndrome

October 18, 2023 — Sequana Medical NV, a pioneer in the treatment of fluid overload in liver disease, heart failure and ...

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University of Cincinnati to partner with UNC, Duke for large prospective study
News | Stroke
Learning More About How Cancer Affects Stroke Risk

October 17, 2023 — Patients with a previous or current cancer diagnosis are more likely to have a stroke than the ...

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Scientists from The Florey are among the world’s leading stroke experts who have mapped out how researchers and clinicians can improve outcomes for people who have survived a stroke.
News | Stroke
International Experts Push for Innovation to Improve Stroke Recovery

October 17, 2023 — Scientists from The Florey are among the world’s leading stroke experts who have mapped out how ...

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Novel platform for structural heart interventions now in human use, with ability to improve patient recovery and reduce anesthesia and hospital stays
News | Cardiovascular Clinical Studies
BioCardia Announces Completion of Enrollment in Phase III CardiAMP HF Trial and Plans for CardiAMP HF Trial II

October 12, 2023 — BioCardia, Inc., a developer of cellular and cell-derived therapeutics for the treatment of ...

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Combination of Tenaya’s HDAC6 inhibitors with Empagliflozin Shows Additive Benefits in Preclinical HFpEF Model and Highlights Differentiated Mechanism of Action
News | Heart Failure
Tenaya Therapeutics Presents Encouraging New Clinical and Preclinical Data from HDAC6 Inhibitor Program TN-301 for the Potential Treatment of Heart Failure with Preserved Ejection Fraction at the 2023 HFSA Annual Scientific Meeting

October 11, 2023 — Tenaya Therapeutics, Inc., a clinical-stage biotechnology company with a mission to discover, develop ...

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Feature | Cardiovascular Clinical Studies | Christine Book
“One on One” with Christine Seidman, MD, FACC, on Hypertrophic Cardiomyopathy

October 11, 2023 — To gain the latest insight into genetic research for the treatment of hypertrophic cardiomyopathy ...

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REBALANCE-HF early feasibility trial met objective of identifying responder group with demonstrated benefits in heart function, hemodynamics, and physical activity at 6 months
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Late-Breaking Data Confirms Safety of Axon Therapies' Innovative Heart Failure Procedure and Identifies Patients Most Likely to Benefit from SAVM Therapy

October 10, 2023 — Axon Therapies, a private company focused on addressing a root cause of heart failure, announced 6 ...

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The study marks a new standard for inclusive medicine with recruitment for target demographics reaching over 3x the national average
News | Cardiovascular Clinical Studies
Hawthorne Effect Announces Monumental Diversity in Patient Recruitment Data for Valvular Heart Disease Study

October 10, 2023 — Hawthorne Effect, a complete clinical trials solution, announced interim recruitment results for the  ...

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Primary endpoint, six-month clinical and imaging data from clinical trial of DESyne BDS Plus stent system evaluating safety and efficacy of localized delivery of anticoagulants and an anti-proliferative agent designed to reduce the implant thrombotic risk
News | Stents Drug Eluting
Elixir Medical To Present Randomized Clinical Dataset Featuring World’s First Triple Drug-Eluting Coronary Implant Eluting Two Anticoagulants and Sirolimus at TCT 2023

October 10, 2023 — Elixir Medical, a developer of innovative cardiovascular technologies, announced it will present ...

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The program is recommended by the Centers for Medicare and Medicaid services for patients who undergo heart valve repair or replacement
News | Heart Failure
TAVR: Less Than One-third of Patients Enter Cardiac Rehab After Heart Procedure

October 9, 2023 — The vast majority of people who have a minimally invasive heart valve replacement procedure do not ...

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Rejuvenate Bio announced new preclinical efficacy data for RJB-0402, a gene therapy targeting key disease-mediating pathways. RJB-0402 demonstrated efficacy in a mouse model of arrhythmogenic cardiomyopathy (ACM)
News | Sudden Cardiac Arrest
Rejuvenate Bio Announces Preclinical Data for Gene Therapy Candidate RJB-0402 for the Treatment of Arrhythmogenic Cardiomyopathy

October 9, 2023 — Rejuvenate Bio announced new preclinical efficacy data for RJB-0402, a gene therapy targeting key ...

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Endotronix announced FDA approval for the PROACTIVE-HF 2 IDE trial with the Cordella Sensor to expand market access and shared positive results from a substudy of their pivotal PROACTIVE-HF clinical trial. The company plans to share full results from the PROACTIVE-HF trial next year.
News | Cardiovascular Clinical Studies
Endotronix Receives IDE Approval for the Market Expanding PROACTIVE-HF 2 Clinical Trial

October 9, 2023 — Endotronix, Inc., a digital health and medical technology company dedicated to advancing the treatment ...

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Retrospective study of over 18,000 drug-refractory AFib patients found those treated with catheter ablation had a 57% lower risk of developing heart failure compared to those receiving antiarrhythmic drugs 
News | Atrial Fibrillation
Biosense Webster Study Links Lower Risk of Heart Failure in Atrial Fibrillation Patients Treated with Catheter Ablation Compared to Antiarrhythmic Drugs

October 6, 2023 — Biosense Webster, Inc., a global leader in cardiac arrhythmia treatment and part of Johnson & Johnson ...

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According to new research published in Mayo Clinic Proceedings, calculating the patient's mean arterial pressure (AugMAP) is a simple and effective way to identify those patients who may benefit from more aggressive treatment strategies.
News | Structural Heart
Mayo Clinic Researchers Develop Calculation to Identify High-risk Moderate Aortic Stenosis Patients

October 5, 2023 — Mayo Clinic researchers have developed a calculation that can help identify moderate aortic stenosis p ...

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Beilinson Hospital in Israel used Nanox.AI’s HealthCCSng solution to conduct study on routine chest CT scans to assess impact of AI-based coronary artery calcium (CAC) measurements
News | Computed Tomography (CT)
Nanox.AI’s HealthCCSng AI Solution Reveals ~60% of Patients in Study had Previously Undetected Risk of a Cardiovascular Event from Routine Chest CTs

September 29, 2023 —Nano-X Imaging, an innovative medical imaging technology company, today announced that HealthCCSng ...

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