Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

New trial results from the international RAPID Trial show that administering a full dose of a standard blood thinner early to moderately ill hospitalized patients with COVID-19 could halt the thrombo-inflammation process and reduce the risk of severe disease and death. How to anticoagulate COVID patients. How to prevent thrombus in COVID patients.

Feature | Coronavirus (COVID-19)

Study Supports Early Anticoagulant Treatment to Reduce Death in Moderately Ill COVID-19 Patients

July 15, 2021 — COVID-19 is marked by heightened inflammation and abnormal clotting in the blood vessels, particularly ...

July 15, 2021

Videos | Structural Heart

VIDEO: Acurate neo2 TAVR Valve Performs Well in Latest Trials

Doctor Andreas Ruck, interventional cardiologist and head of the mitral/tricuspid program, Karolinska University ...

July 14, 2021

An example of a strain echo from the study showing reduced peak longitudinal/reservoir left atrial strain in a COVID-19 patient who developed atrial fibrillation during admission. Average left atrial strain here is 20% (normal should be above 38%).

News | Cardiovascular Ultrasound

Speckle Tracking Strain Echo May Predict Heart Complications From COVID-19

July 13, 2021 — Researchers at Johns Hopkins Medicine have shown that speckle-tracking strain echocardiograms may ...

July 14, 2021

The Xeltis synthetic polymer restorative pulmonary valve is implanted surgically and acts as a scaffold for the patient's own cells to proliferate. The valve and conduit then bioresorbs over time, leaving behind a new valve made from the patient's own cells. The hope is this will reduce or eliminate the need for numerous repeat surgeries as a pediatric patient grows.

Feature | Heart Valve Technology

Xeltis Begins Pivotal Trial for Pulmonary Valve That Grows With the Patient

July 8, 2021 – Xeltis announced it started the first pivotal trial for a synthetic polymer restorative pulmonary valve ...

July 08, 2021

Videos | Artificial Intelligence

VIDEO: Artificial Intelligence Identifies High-Risk COVID Patients From Cardiac Ultrasounds

Federico Asch, M.D., FASE, director of cardiovascular core labs, cardiovascular imaging, MedStar Health Research ...

July 01, 2021

News | Womens Cardiovascular Health

3 Studies Show How Echocardiography is a Key Tool in Women's Health

June 29, 2021 – Three research studies presented at the American Society of Echocardiography (ASE) 2021 virtual meeting ...

June 29, 2021

Images from the ASE presentation. Left, UEA echo showing focal narrowing of the SCPC anastomosis and the same view on invasive angiography. Right, UAE echo showing complete occlusion of pulmonary artery and angiography showing the same view.

News | Congenital Heart

Ultrasound Contrast Agents Greatly Aids in Complex Congenital Heart Imaging

June 29, 2021 – Echocardiography with ultrasound enhancing agents (UEAs) has proven to be a valuable imaging procedure ...

June 29, 2021

Researchers analyzing surveillance data on 518 children and adolescents with MIS-C who were admitted to U.S. hospitals in 2020 fopiund those treated with intravenous immune globulin (IVIG) plus glucocorticoids had a lower risk of new or persistent cardiovascular dysfunction than IVIG alone. Left photo Getty Images, right photo Nemours Children’s Health System.

News | Coronavirus (COVID-19)

Study Provides MIS-C Treatment Guidance To Avoid Cardiovascular Dysfunction

June 28, 2021 - A recent analysis found that children and adolescents with multisystem inflammatory syndrome in children ...

June 28, 2021

A small number of patients develop myocarditis after receiving the messenger RNA (mRNA) COVID-19 vaccines from Pfizer and Moderna. This recently raised concerns after numbers for this adverse reaction jumped in April and May, prompting review this week by the Centers for Disease Control and Prevention (CDC) Advisory Committee on the Immunization Practices (ACIP).

Feature | Coronavirus (COVID-19) | By Dave Fornell, Editor

Overview of Myocarditis Cases Caused by the COVID-19 Vaccine

A small number of patients develop inflammation leading to myocarditis after receiving the messenger RNA (mRNA) COVID-19 ...

June 24, 2021

Clinical trial quality data can be derived from national cardiovascular registries, which may change how trials are performed in the future.

News | Cardiovascular Clinical Studies

Study Shows ACC Registry Data Could Support Cardiac Clinical Trials

June 24, 2021 — Data captured in American College of Cardiology (ACC) National Cardiovascular Data Registry (NCDR) regis ...

June 24, 2021

Feature | Coronavirus (COVID-19)

Small Number of Patients Have Myocarditis-like Illness After COVID-19 Vaccination

June 23, 2021 — Findings from a small study detailing the treatment of myocarditis-like symptoms in seven people after ...

June 23, 2021

The Philips Healthcare SyncVision system co-registers iFR hemodynamic blood flow measurements to live angiograms to enable easier assessment of which lesions in a vessel need to be stented and which can be left alone and treated medically.

News | FFR Technologies

First Patient Enrolled in DEFINE GPS Study to Assess PCI Guided by Co-registered iFR Versus Angiography

June 22, 2021 – Philips Healthcare announced the official start of the DEFINE GPS study, with the first patient being ...

June 22, 2021

Boston Scientific Makes a Comeback With Positive Clinical Data With its Second Iteration Acurate neo2 TAVR Valve

Blog | Structural Heart

Boston Scientific Makes a Comeback With Positive Clinical Data for its Second Iteration Acurate neo2 TAVR Valve

It is brutal and very expensive to bring a new transcatheter valve to market. Boston Scientific invested vast amounts of ...

June 08, 2021

Some of the top technology news from ACC 2021. Top left, the LAAOS III trial showed benefit when surgeons seal off the LAA during other open heart procedures. Bottom left, the ReCor Paradise renal denervation system helped lower blood pressure in patients who did not respond to medication. Top right, for patients with both heart failure and AFib it makes no differences is therapy is focused on controlling the heart rhythm or heart rate. Bottom right, the FLOWER-MI trial found no benefit to FFR-guided PCI.

Feature | ACC | By Dave Fornell, Editor

Key Cardiology Technology Takeaways at ACC 2021

Here are the top 10 takeaways from the late-breaking studies on cardiovascular technologies presented at the 2021 Americ ...

June 08, 2021

Two years ago a study raised concerns that paclitaxel-coated devices may cause increased mortality in peripheral artery disease patients. However, numerous studies now show there is no risk of increased mortality. The most recent study is the SAFE-PAD study presented at ACC.21.

News | Peripheral Artery Disease (PAD)

SAFE-PAD Study Shows No Safety Issues With Paclitaxel-coated Devices In Peripheral Artery Disease

June 7, 2021 — A couple years ago a study showed a mortality safety signal in patients who underwent peripheral artery ...

June 07, 2021