Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

An independent analysis of Lutonix 035 drug-coated balloon (DCB) patient-level data showed no statistically significant mortality increase. This was one of the first major reviews of trial data for patients who were treated with a paclitaxel coated device used in peripheral vessels following a meta analysis study of paclitaxel device trials published in December 2018 that showed a mortality safety signal. This was a major discussion during the FDA townhall meeting at the #TCT2019.

News | Drug-Eluting Balloons

LEVANT Trial Data Shows Safety of Drug-Coated Balloon Shown

October 10, 2019 — An independent analysis of Lutonix 035 drug-coated balloon (DCB) patient-level data showed no ...

October 10, 2019

BackBeat CNT is the flagship therapy of Orchestra BioMed Inc. It is a bioelectronic treatment that immediately, substantially and chronically lowers blood pressure (BP) while simultaneously modulating the autonomic nervous system (ANS).

News | Hypertension

MODERATO II Study: Cardiac Neuromodulation Significantly Reduces Systolic Blood Pressure

October 10. 2019 — Late-breaking results from its MODERATO II double-blind, randomized study of BackBeat Cardiac ...

October 10, 2019

Videos | Antiplatelet and Anticoagulation Therapies

VIDEO: TWILIGHT Trial Shows Benefit to Ticagrelor Monotherapy After Stent Implantation

Roxana Mehran, M.D., FACC, FACP, FCCP, FESC, FAHA, FSCAI, professor of medicine and director of interventional ...

October 10, 2019

Feature | TCT

TCT 2019 Late-breaking Presentations

October 10, 2019 — Here are the Cardiovascular Research Foundation (CRF) 12 late-breaking trials and 16 late-breaking ...

October 11, 2019

News | Stent Grafts

PQ Bypass Granted IDE Approval to Start TORUS SFA Stent Graft Pivotal Study

October 8, 2019 — PQ Bypass Inc. announced it has received full approval of its investigational device exemption (IDE) ...

October 08, 2019

Videos | Antiplatelet and Anticoagulation Therapies

VIDEO: Overview of Short DAPT in High-risk Bleeding Patients Who Receive Stents

American Heart Association President Robert Harrington, M.D., interventional cardiologist and the Arthur L. Bloomfield ...

October 08, 2019

Videos | Cardiogenic Shock

VIDEO: Cardiogenic Shock Initiative Continues to Reduce Mortality by 50 Percent

William O’Neill, M.D., medical director of the Center for Structural Heart Disease at Henry Ford Hospital, Detroit ...

October 08, 2019

Heart MRI example. An example of a cardiac MRI exam showing perfusion defects in the heart muscle, amount of infarct and edema and a score for myocardial salvage which can help determine if revasularization will help restore heart function.

News | Magnetic Resonance Imaging (MRI)

Cardiac MRI Delivers Accurate Diagnosis for Frontline Chest Pain Evaluation

October 7, 2019 – A recent study published in the New England Journal of Medicine supports the use of cardiac magnetic ...

October 07, 2019

Videos | TCT

VIDEO: SCAI Prospective on Key Takeaways at TCT 2019

Chandan Devireddy, M.D., offers insights about what he saw as the top take aways from the 2019 Transcatheter ...

October 04, 2019

News | Heart Valve Technology

Study Finds Sustained Benefit for TAVR vs. SAVR at One Year

October 4, 2019 – A new analysis of the PARTNER 3 Trial data found a modest, but significant, improvement in one-year ...

October 04, 2019

The COAPT Economic Analysis sub-study found it is cost effective to treat heart failure patients who have severe secondary mitral regurgitation with MitraClip to reduce their MR symptoms. #TMVR #TCT2019 #TCT19

News | Heart Failure

Transcatheter Mitral Valve Repair is Cost-Effective in Heart Failure Patients

October 4, 2019 – Results of a new economic analysis of the COAPT Trial data found that transcatheter mitral valve ...

October 04, 2019

RenalGuard Therapy was found to be superior to the POSEIDON method in preventing contrast-induced acute kidney injury (CI-AKI) for patients with kidney disease who undergo interventional cath lab procedures. Results of the 700 patient, randomized, investigator-driven REMEDIAL III Trial presented at the 2019 Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. #TCT19 #TCT2019

News

Contrast-Induced Kidney Injury Prevented With RenalGuard in REMEDIAL III Trial

October 4, 2019 – RenalGuard Therapy was found to be superior to the POSEIDON method in preventing contrast-induced ...

October 04, 2019

Five-year results from the PARTNER 2A Trial found patients with severe aortic stenosis (AS) and intermediate surgical risk who underwent Sapien 3 transcatheter aortic valve replacement (TAVR) had similar rates of death and disabling stroke compared to those who had surgical aortic valve replacement (SAVR). However, TAVR using a transthoracic approach had poorer outcomes compared to SAVR. #TCT2019

News | Heart Valve Technology

October 3, 2019 – Five-year results from the PARTNER 2A Trial found patients with severe aortic stenosis (AS) and ...

October 03, 2019

People watch the presentation of the five-year EXCEL Trial data by Gregg Stone, M.D., live in the Abbott booth at TCT 2019. Abbott makes the Xience stent used in the trial, which compared equally with long term surgical outcomes. #TCT2019

Feature | Cath Lab

Left Main Treated With PCI or CABG Have Similar Outcomes at Five Years

October 3, 2019 – Five-year data from the EXCEL Trial showed patients with left main coronary disease treated with ...

October 03, 2019

COAPT Trial three-year data show the MitraClip continued effectiveness in heart failure patients with secondary mitral reguritation. #TCT2019 #TCT19 #mitralclip

News | Heart Failure

COAPT Three-year Data Show Continued Effectiveness in Heart Failure Patients

October 3, 2019 – The three-year results from the COAPT Trial demonstrated that reducing severe secondary mitral ...

October 03, 2019