Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

University of Virginia School of Medicine researchers have discovered a gene on the Y chromosome that contributes to the greater incidence of heart failure in men.

News | Heart Failure

New Advance Against a Form of Heart Failure Prevalent in Men

April 12, 2024 — University of Virginia School of Medicine researchers have discovered a gene on the Y chromosome that ...

April 12, 2024

Trial bolsters evidence that less invasive strategy is safe and effective in younger, lower-risk patients

News | Cardiovascular Clinical Studies

TAVR Found Non-Inferior to SAVR for Low-Risk Patients

April 11, 2024 — Transcatheter aortic valve replacement (TAVR) was found to bring no increased risks and was associated ...

April 11, 2024

PCI shows substantial benefits over medications alone

News | Cardiovascular Clinical Studies

Preventive Percutaneous Coronary Intervention for High-Risk Coronary Plaques Reduces Cardiac Events

April 11, 2024 — People with a buildup of fatty atherosclerotic plaque in the heart’s arteries considered at risk of ...

April 11, 2024

Results from the IVUS-DCB trial were recently presented at the American College of Cardiology Annual Scientific Session, ACC.24.

News | ACC

Intravascular Ultrasound Outperforms Angiography for Peripheral Artery Disease Treatment

April 11, 2024 — One-year success rates from angioplasty procedures to open clogged arteries in the legs were ...

April 11, 2024

Subanalysis finds benefit for patients not on heart-beneficial antidiabetic medication

News | Cardiovascular Clinical Studies

New Drug Fails to Improve Diabetes-Related Heart Failure

April 9, 2024 — One of the first studies to attempt to treat early-stage heart failure in patients with Type 2 diabetes ...

April 09, 2024

Phase 2 trial shows early signs that the investigational drug could relieve symptoms and improve exercise capacity in HCM patients with no other evidence-based treatment options available

News | Cardiovascular Clinical Studies

Ninerafaxstat Well-Tolerated and Safe for Nonobstructive Hypertrophic Cardiomyopathy

April 9, 2024 — The investigational drug ninerafaxstat showed a good tolerability and safety profile, along with ...

April 09, 2024

Trial shows increased risk of bleeding with topical administration during open heart surgery

News | Cardiovascular Clinical Studies

Topical Tranexamic Acid Found Inferior to Intravenous Administration

April 9, 2024 — Administering tranexamic acid (TxA), a drug used to reduce bleeding during heart surgery, topically ...

April 09, 2024

Study found no difference in troponin biomarkers up to one month after anthracycline treatment

News | Cardiovascular Clinical Studies

ACE Inhibitor Not Protective Against Heart Damage from Chemotherapy

April 9, 2024 — Patients who took an angiotensin-converting enzyme (ACE) inhibitor while undergoing cancer treatment ...

April 09, 2024

Participants saw 35% reduction in LDL cholesterol, signaling the process could offer safe, effective non-prescription use of life-saving drug

News | Cardiovascular Clinical Studies

Study Shows Web App Effective in Determining Access to Statins Without a Prescription

April 9, 2024 — Using a web application to qualify individuals for treatment with a nonprescription statin closely ...

April 09, 2024

First head-to-head comparison of leading valve types finds better valve performance with selfexpanding valve and non-inferior clinical outcomes at one year

News | Cardiovascular Clinical Studies

Self-Expanding Valve Outperforms Balloon-Expandable Valve for TAVR in Patients with Small Valve Annulus

April 9, 2024 — People with a small aortic annulus, a part of the heart’s anatomy where the left ventricle meets the ...

April 09, 2024

Infusions reduce lead levels but show no effect on clinical endpoints

News | Cardiovascular Clinical Studies

Chelation Therapy Does Not Improve Outcomes after Heart Attack

April 8, 2024 — People with diabetes who had suffered a heart attack derived no clinical benefit from edetate disodium ...

April 08, 2024

$Study suggests routine use is likely unnecessary for those with normal ejection fraction$

News | Cardiovascular Clinical Studies

Beta Blockers May Not Benefit Many Heart Attack Survivors

April 8, 2024 — Taking beta blockers after a heart attack did not significantly reduce the risk of death or a second ...

April 08, 2024

Mechanical circulatory support boosts survival in cardiogenic shock patients, despite risks

News | Cardiovascular Clinical Studies

Heart Pump Improves Survival After Severe Heart Attacks

April 8, 2024 — Implantation of the Impella CP micro-axial flow pump in the hours after a heart attack significantly ...

April 08, 2024

Ticagrelor alone outperforms 12-month DAPT for reducing bleeding with no increased risk

News | Cardiovascular Clinical Studies

Study Suggests Most Patients with Acute Coronary Syndromes Can Safely Stop Aspirin One Month After Percutaneous Coronary Intervention

April 8, 2024 — People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin ...

April 08, 2024

Earning points or small sums of money encourages people to ‘step up’ their physical activity

News | Cardiovascular Clinical Studies

Incentives Prompt Increased Daily Walking in Patients at Risk for Heart Disease

April 7, 2024 — Strategies such as earning points or small amounts of money encouraged people at high risk for heart ...

April 07, 2024