Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

A new Cedars-Sinai study is the first study proven to be effective at identifying coronary artery disease patients at highest risk for sudden cardiac death. Photo by Cedars-Sinai.

News | Sudden Cardiac Arrest

Genetic Score Detects Those at Risk for Sudden Cardiac Death

August 26, 2022 — Researchers in the Smidt Heart Institute at Cedars-Sinai are one step closer to identifying patients ...

August 26, 2022

News | PET Imaging

Late Breaking Flurpiridaz Trial Results at ASNC2022

August 25, 2022 — The results of “A Phase 3, Open-label, Multicenter Study of Flurpiridaz (F18) Injection for Positron ...

August 25, 2022

Imperfect current propagation in the heart is at the root of most cardiac diseases

News | Cardiac Imaging

Measuring Currents in the Heart at Millimeter Resolution with a Diamond Quantum Sensor

August 25, 2022 — Imperfect current propagation in the heart is at the root of most cardiac diseases. Thanks to a novel ...

August 25, 2022

Dr. Jonathan Roberts is medical director of Clinical Research and Education, Interventional Cardiology for Memorial Healthcare System and program director of its Cardiology Fellowship program.

News | Heart Failure

Congestive Heart Failure Patients May Be Eligible for Treatment that Could Help Them Live Longer

August 24, 2022 — Patients diagnosed with moderate aortic stenosis and congestive heart failure may qualify to ...

August 24, 2022

The first US patient has been enrolled in the FDA SELUTION4BTK (Below-the-Knee) clinical trial evaluating SELUTION SLR, MedAlliance’s novel sirolimus-eluting balloon.

News | Drug-Eluting Balloons

First US Patient Enrolled in SELUTION SLR IDE Peripheral Study

August 23, 2022 — The first US patient has been enrolled in the FDA SELUTION4BTK (Below-the-Knee) clinical trial ...

August 23, 2022

A first-in-human multicenter trial involving Mayo Clinic used a new ablation technique for patients with ventricular tachycardia, an abnormally rapid heart rhythm that is a leading cause of sudden cardiac death worldwide

News | Implantable Cardioverter Defibrillator (ICD)

First-in-Human Trial Shows Promise for Hard-to-Treat Ventricular Tachycardia Heart Rhythms

August 18, 2022 — A first-in-human multicenter trial involving Mayo Clinic used a new ablation technique for patients ...

August 18, 2022

Histological analysis comparing the size of the heart of a normal mouse (left) and a mouse lacking the protein MKK6 (right). Image courtesy of CNIC

News | Cardiovascular Clinical Studies

CNIC Scientists Uncover Opposing Roles of p38 Proteins in Cardiac Hypertrophy

August 17, 2022 — A study carried out by scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) ...

August 17, 2022

Researchers at Ochsner Health and Tulane University School of Medicine have identified the genes that become active in carotid arteries when plaque rupture causes a stroke.

News | Stroke

Ochsner and Tulane Collaboration Uncovers What Happens to Genes Inside Artery Plaques to Trigger Strokes

August 15, 2022 — Researchers at Ochsner Health and Tulane University School of Medicine have identified the genes that ...

August 15, 2022

A new model developed by researchers can be used for a myriad of applications, most notably to evaluate the safety and efficacy of drugs on the cardiovascular system

News | Artificial Heart

Creating an 'Adult-Like' Mature Human Cardiac Tissue

August 15, 2022 — Researchers in the Biomedical Engineering Department at UConn have developed a new cardiac cell ...

August 15, 2022

News | ASNC

Flurpiridaz Clinical Trial Results Will be Announced at ASNC2022

August 12, 2022 — The results of “A Phase 3, Open-label, Multicenter Study of Flurpiridaz (F18) Injection for Positron ...

August 12, 2022

Older adults with atrial cardiopathy (a major, often undetected cardiac cause of stroke) may be at increased risk of developing dementia, according to new research led by Johns Hopkins Medicine.

News | Cardiovascular Clinical Studies

Johns Hopkins Researchers Find Link Between Dementia and Atrial Cardiopathy

August 12, 2022 — Older adults with atrial cardiopathy (a major, often undetected cardiac cause of stroke) may be at ...

August 12, 2022

Effect of chronic reductive stress on myocardial proteome.

News | Cardiovascular Clinical Studies

The Protein Signature Changes During Heart Disease Caused by Reductive Stress

August 8, 2022 — Two years ago, University of Alabama at Birmingham researchers and colleagues reported that reductive ...

August 08, 2022

The condition is known to increase the risk of cardiovascular disease and atherosclerosis, a buildup of fats inside the blood vessels that can constrict blood flow to the body’s tissues.

News | Heart Failure

Study Reverses Long-Held Ideas About Relationship Among Diabetes, Fat and Cardiovascular Disease

August 8, 2022 — A major risk factor for diabetes, insulin resistance occurs when the cells of the body do not respond ...

August 08, 2022

The illustration shows a portion of the receptor pGC-A, known as the extracellular domain, which protrudes from cell surfaces in the cardiovascular system. Small molecules bind with the receptor and exert subtle control over blood pressure. The new research offers the first sneak peek at the full-length receptor, a vital step in the development of new drugs to treat hypertension and other afflictions.

News | Hypertension

New Study Explores Cell Receptor Crucial for Cardiovascular Health

August 8, 2022 — Cardiovascular diseases remain a leading cause of death around the world. A primary contributor to ...

August 08, 2022

About one percent of the world population is born with a congenital heart defect, which affects about 40,000 U.S. births each year, but how these particular birth defects come about is largely unknown.

News | Congenital Heart

New Study Provides Insight for How Congenital Heart Defects Manifest

August 2, 2022 — About one percent of the world population is born with a congenital heart defect, which affects about ...

August 02, 2022