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Tendyne Holdings Inc. has secured $25 million in an oversubscribed Series C financing led by Apple Tree Partners, along with Boulle Group members and other existing investors.

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Cytori Stem Cell Therapy Heart Failure Treatments PRECISE Trial
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Cytori Therapeutics announced publication of safety and efficacy data from a 36 month European clinical trial of Cytori Cell Therapy in patients with chronic ischemic heart failure.

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April 18, 2014 — New research presented at the 34th annual meeting of the International Society for Heart and Lung Transplantation (ISHLT) demonstrated the CorMatrix particulate extracellular matrix (P-ECM) alone and as an adjunct to HeartWare International Inc.’s left ventricular assist device (LVAD) improved cardiac function in a bovine ischemic heart failure model, as compared to LVAD alone.

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April 18, 2014 — A University of California, San Diego scientist has developed a new biomaterial that could potentially treat heart attacks. Karen Christman, Ph.D., associate professor of bioengineering at UC San Diego Jacobs School of Engineering, has been at work on a new injectable hydrogel, which is designed to repair damaged cardiac tissue following a heart attack.

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April 18, 2014 — AliveCor announced the online publication of study results of the SEARCH-AF study. The SEARCH-AF study, conducted in Australia, screened 1,000 customers over 65 years old for atrial fibrillation (AF) in 10 community pharmacies in suburban Sydney.

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Technology

Medtronic announced the U.S. Food and Drug Administration (FDA) approved an expanded indication for biventricular (BiV) pacing with Medtronic cardiac resynchronization therapy-pacemakers and -defibrillators (CRT-P and CRT-D). Medtronic CRT devices are now approved to treat patients with atrioventricular (AV) block and left ventricular (LV) systolic dysfunction, reducing heart failure hospitalizations and mortality, and improving cardiac function in these patients.

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Toshiba America Medical Systems Inc. received approval to operate (ATO) with the U.S. Air Force, making Toshiba the only current manufacturer to have a fully certified computed tomography (CT) system for use on the Air Force Network.

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Data presented from two meta-analyses using the Atherotech Vertical Auto Profile (VAP) lipid panel showed the impact high-density lipoprotein (HDL) cholesterol and remnant lipoprotein (RLP) cholesterol have on determining a patient’s risk for hard coronary heart disease (CHD) endpoints, such as myocardial infarction or coronary death.

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ACC 14 Clinical Trial Women Diet Drinks Cardiovascular Problem Mortality
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Healthy postmenopausal women who drink two or more diet drinks a day may be more likely to have a heart attack, stroke or other cardiovascular problems, according to research to be presented at the American College of Cardiology’s 63rd Annual Scientific Session.

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April 16, 2014 — Covidien announced it has notified customers of a voluntary recall to address an issue with certain lots of its Pipeline embolization device and Alligator retrieval device, where the polytetrafluoroethylene (PTFE) coating applied to the delivery wire could delaminate and detach from the devices.

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April 16, 2014 — Abbott announced it has completed enrollment of three clinical trials to support approvals of the company's Absorb bioresorbable vascular scaffold (BVS) in the United States, Japan and China. Combined, the U.S., Japan and China account for more than 50 percent of the world's heart stent market. Absorb received CE mark in 2011 and is available in more than 60 countries around the world.

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Biotronik announced that the first patients across the United States have received implants of the new Iforia implantable cardioverter-defibrillators (ICDs).

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Patients with peripheral artery disease in the upper leg experienced significantly better outcomes at 12 months after treatment with the IN.PACT Admiral drug-coated balloon from Medtronic Inc. than with standard balloon angioplasty, according to a landmark clinical study reported on today for the first time.

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Corevalve beats surgery, ACC 2014, TAVR vs surgery, Edwards lawsuit
Feature | Dave Fornell

The U.S. District Court for the District of Delaware granted a preliminary injunction limiting the sale of Medtronic's CoreValve transcatheter aortic valve replacement (TAVR) system in the United States. The court ordered the injunction April 10.

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Technology

April 15, 2014 — The Spectranetics Corp. announced U.S. Food and Drug Administration (FDA) clearance of two new mechanical lead extraction platforms that expand physicians' options for the safe removal of cardiac leads. Each incorporates innovative designs for mechanical extraction aimed at providing total lead management solutions.

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