May 9, 2017 — A manuscript by physicians from Mayo Clinic and Harvard Brigham & Women's Hospital entitled, “Initial Experience with the BioSig Pure EP Signal Recording System: An Animal Laboratory Experience,” was published in The Journal of Innovations in Cardiac Rhythm Management (JICRM), April 2017 issue. Read the article by clicking here.
Initial results and solutions offered by the Pure EP System are highlighted in several main categories:
• Saturation artifact
• Clipping/Overlapping of signals
• Noise due to ablation
• Unipolar signals
• Contact force
• Poor catheter visualization
• Conduction tissue signal recording
“BioSig is very grateful to collaborate with key opinion leaders in the EP field,” said BioSig Executive Chairman Kenneth Londoner “This collaboration, together with preclinical data derived from studies conducted from 2015 to date, have produced very significant results to help the Company strengthen its positioning statement for the Pure EP System. The findings in this publication clearly show the need for expanding the boundaries in recording cardiac signals in the electrophysiology lab. Our system demonstrated abilities to produce great recordings from legacy catheters (Boston Scientific and Johnson & Johnson) and enhanced recordings compared to existing recording and mapping systems. One of the most important findings is Pure EP System’s ability to record high quality unipolar signals and current of injury (COI), which can complement data obtained using a contact force-sensing catheter.”
For more information: www.biosigtech.com
April 29, 2025 
