Pankaj Garg, MD
July 12, 2024 — Researchers have developed a groundbreaking method for analyzing heart MRI scans with the help of artificial intelligence, which could save valuable NHS time and resources, as well as improve care for patients.
The teams from the Universities of East Anglia (UEA), Sheffield and Leeds created an intelligent computer model that utilizes AI to examine heart images from MRI scans in a specific view known as the four-chamber plane.
Lead researcher Dr Pankaj Garg, of the University of East Anglia’s Norwich Medical School and a consultant cardiologist at the Norfolk and Norwich University Hospital, heads up a team of researchers who have pioneered innovative and revolutionary 4D MRI imaging technology. This is paving the way for faster, non-invasive and more accurate diagnosis of heart failure and other cardiac conditions.
Garg said: “The AI model precisely determined the size and function of the heart's chambers and demonstrated outcomes comparable to those acquired by doctors manually but much quicker.
“Unlike a standard manual MRI analysis, which can take up to 45 minutes or more, the new AI model takes just a few seconds.
“This automated technique could offer speedy and dependable evaluations of heart health, with the potential to enhance patient care.”
The retrospective observational study consisted of data from 814 patients from Sheffield Teaching Hospitals NHS Foundation Trust and Leeds Teaching Hospitals NHS Trust, which was then used to train the AI model.
To make sure the model’s results were accurate, scans and data from another 101 patients from the Norfolk and Norwich University Hospitals NHS Foundation Trust were then used for testing.
While other studies have investigated the use of AI in interpreting MRI scans, this latest AI model was trained using data from multiple hospitals and different types of scanners, as well as conducting the testing on a diverse group of patients from a different hospital. In addition, this AI model provides a complete analysis of the entire heart using a view that shows all four chambers, while most earlier studies focused on a view that only looks at the heart's two main chambers.
PhD student Hosamadin Assadi, of UEA’s Norwich Medical School, said: “Automating the process of assessing heart function and structure will save time and resources and ensure consistent results for doctors.
“This innovation could lead to more efficient diagnoses, better treatment decisions, and ultimately, improved outcomes for patients with heart conditions.
“Moreover, the potential of AI to predict mortality based on heart measurements highlights its potential to revolutionize cardiac care and improve patient prognosis.”
The researchers say future studies should test the model using larger groups of patients from different hospitals, with various types of MRI scanners, and including other common diseases seen in medical practice to see if it works well in a broader range of real-world situations.
Other recent research from the teams at UEA, Leeds and Sheffield has refined the method of using heart MRI scans for female patients, particularly for those with early or borderline heart disease, which meant that 16.5pc more females were able to be diagnosed.
The research was a collaboration between the University of East Anglia, the University of Leeds, the University of Sheffield, Leiden University Medical Centre, the Norfolk and Norwich University Hospitals NHS Foundation Trust, Sheffield Teaching Hospitals NHS Foundation Trust and Leeds Teaching Hospitals NHS Trust.
The study was supported by funding for Dr Pankaj Garg from the Wellcome Trust Clinical Research Career Development Fellowship.
'Development and validation of AI-derived segmentation of four-chamber cine CMR' is published in the European Radiology Experimental.
For more information: www.uea.ac.uk
February 21, 2024 
