Heart Failure

This heart failure channel offers news and new technology to treat heart failure. This includes for new innovations to treat congestive heart failure (CHF). The channel includes news on HFpEF and HFrEF. Heart failure occurs when the heart is no longer able to pump as much blood as the body requires. This can lead to enlargement of the heart because the muscle works harder to supply blood, but the pumping is ineffective. This may be due to defects in the myocardium, such as an infarct, or due to structural issues such as severe valve regurgitation. The disease is divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant  or a left ventricular assist device (LVAD).

Allogeneic CardiALLO therapy for heart failure to complement autologous cell therapy currently enrolling in Phase III CardiAMP Heart Failure clinical trial
News | Heart Failure
BioCardia Announces FDA Approval of IND Application for Allogeneic NK1R+ Human Mesenchymal Stem Cells for Ischemic Heart Failure

December 7, 2022 —   BioCardia, Inc., a developer of cellular and cell-derived therapeutics for the treatment of ...

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News | Cardiovascular Business
Ultromics Receives FDA Clearance for AI-based Platform for Echocardiography

December 7, 2022 — Ultromics has announced that its EchoGo Heart Failure, an artificial intelligence (AI) platform for ...

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Ms. Nieves, donor family, and doctors. Photo courtesy of Montefiore Health System.
News | Heart Failure
World's First HIV-Positive to HIV-Positive Heart Transplant Recipient Meets Donor Family, Shares Gratitude for Life & Advocates for Organ Donation

December 2, 2022 —  Westchester resident, 62-year-old Miriam Nieves, is especially grateful this Thanksgiving season ...

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Last year, U.S. Congressman Andy Barr (KY-06) introduced this legislation in the House to honor the legacy of his wife, Carol Leavell Barr, who passed away tragically from sudden cardiac death brought on by mitral valve prolapse, an underlying heart condition that causes death in .2% of cases.
News | Heart Failure
CAROL Act Will Prioritize Research on Heart Valve Disease

December 2, 2022 —  The U.S. Senate today passed the bipartisan Cardiovascular Advances in Research and Opportunities ...

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Transverse heart sections from wild type mice (WT) and transgenic mice overexpressing beta-3 adrenergic receptor in cardiomyocytes (c-hB3tg) after 3 months of aortic stenosis (transaortic constriction, TAC) or control (sham). Hypertrophy after TAC was less severe in the transgenic mice. Courtesy of CNIC
News | Heart Failure
A New Therapeutic Target for the Prevention of Heart Failure Due to Aortic Stenosis

December 1, 2022 —  Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a new ...

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Figure 1. Normal chest X-ray
News | Cardiac Imaging
AI Predicts Heart Disease Risk Using Single X-Ray

November 29, 2022 — Researchers have developed a deep learning model that uses a single chest X-ray to predict the 10 ...

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Tanya Therapeutics announced today that the US FDA has granted orphan drug designation for its second gene therapy product candidate, TN-401, for the treatment of arrhythmogenic right ventricular cardiomyopathy (ARVC)
News | Pharmaceuticals
Tenaya Therapeutics Receives Orphan Drug Designation from the U.S. Food and Drug Administration for its Gene Therapy for Genetic Arrhythmogenic Right Ventricular Cardiomyopathy

November 28, 2022 – Tenaya Therapeutics, a clinical-stage biotechnology company with a mission to discover, develop and ...

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Survivors face higher risk of cardiac events that can reduce their life expectancy by decades
News | Coronavirus (COVID-19)
Study Finds That Risk of Myocarditis After SARS-CoV-2 Vaccination is Increased But Very Low

November 25, 2022 —  A large study found that myocarditis after SARS-CoV-2 vaccination was rare but higher in younger ...

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New research by Cedars-Sinai investigators supports evidence that social factors, such as unemployment, financial difficulties, racial discrimination and other stressors, affect an individual's health. Getty Images
News | Stroke
Racism, Stress and Stroke Outcomes

November 22, 2022 — investigators from the Department of Neurology at Cedars-Sinai have new information on stroke-relate ...

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Trial Evaluates FDA-Designated Breakthrough Therapy for Patients Who Lack Treatment Options
News | Heart Failure
Impulse Dynamics Announces First Patient Enrolled in AIM HIGHer — Implantable Device Trial to Treat Heart Failure in Higher EF Population

November 22, 2022 — Impulse Dynamics, a global medical device company dedicated to improving the lives of people with ...

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UH Cleveland Medical Center. Image courtesy of University Hospitals
News | Deep Vein Thrombosis (DVT)
Four Prospective, Multicenter Studies Support Use of Drug-Coated Balloons Over Bare Metal Stents in Treating Femoropopliteal Lesions

November 21, 2022 —  New research published in the Journal of the American College of Cardiology shows the use of drug ...

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Cardiovascular disease remains the leading cause of death in the United States (US) and worldwide, according to the American Heart Association.
News | Heart Failure
Defining preventive cardiology: A clinical practice statement from the American Society for Preventive Cardiology

November 21, 2022 — Cardiovascular disease remains the leading cause of death in the United States (US) and worldwide ...

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Justin Balko, PharmD, PhD, Ingram Associate Professor of Cancer Research, and a co-corresponding author of the study. Credit: Vanderbilt University Medical Center
News | Heart Failure
Cardiac antigen identified as mechanism for heart complication with immunotherapy-related myocarditis

November 22, 2022 — Myocarditis is a complication that can occur in cancer patients treated with immune checkpoint ...

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Certain adults with this artery-blocking condition may see more benefits with an open bypass compared to less-invasive procedures to improve circulation.
News | Peripheral Artery Disease (PAD)
Bypass Surgery Favorable for Initial Treatment of Chronic Limb-Threatening Ischemia

November 15, 2022 Performing open bypass surgery to restore circulation for people with a severe form of peripheral ...

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UMSOM researchers display first genetically modified pig heart transplanted into living patient. Image courtesy of University of Maryland School of Medicine
News | Heart Failure
Unexpected Electrical Changes Seen in First Successful Transplant of Genetically-Modified Pig Heart

November 15, 2022 — Ten months after transplanting the first genetically-modified pig heart into a human patient ...

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