AstraZeneca announced positive full results from the DECLARE-TIMI 58 cardiovascular (CV) outcomes trial (CVOT) for Farxiga (dapagliflozin) as a late-breaking abstract at the American Heart Association (AHA) Scientific Sessions 2018, Nov. 10-12 in Chicago. Results were simultaneously published in the New England Journal of Medicine (NEJM).

A study in the current edition of the New England Journal of Medicine shows that a particular treatment significantly reduced cardiovascular events, including cardiovascular death, in patients who continue to have high triglyceride levels on statin therapy. These findings could lead to a more effective and life-saving treatment option when used with other combinations of drugs to treat cardiovascular disease.

The Vascade MVP vascular closure system met its endpoints compared to manual compression in a pivotal clinical study for multi-access venous closure following electrophysiology (EP) procedures, according to manufacturer Cardiva Medical Inc. The AMBULATE study is the first randomized pivotal trial of vessel closure conducted exclusively by EP physicians.

Wearable cardiac biosensor developer Cardiac Insight Inc. has partnered with VivoSense, specializing in integration and specialized analysis of wearable sensor data for research and clinical trials. Together, both companies will deliver enhanced research analytics to help VivoSense expand the use of wearable biosensors for pharmaceutical clinical trials and other healthcare applications.

The American College of Cardiology (ACC), the American Heart Association (AHA) and the Heart Rhythm Society (HRS) released a guideline for the evaluation and treatment of patients with bradycardia, or a slow heartbeat, and cardiac conduction disorders.